Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 19996생성일: 2026년 10월 25일
Dimethylformamide → (E)-3-(4-hydroxy-3-methoxyphenyl)-2-propenoic acid 4-nitrooxybutyl ester
https://huagongshe.com/reaction/19996
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Dimethylformamide | HCID 6228 | — |
| 반응물 | 4-Bromobutyl nitrate | HCID 10420252 | — |
| 반응물 | potassium (E)-3-(4-hydroxy-3-methoxyphenyl)-2-propenoate | HCID 23676777 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | (E)-3-(4-hydroxy-3-methoxyphenyl)-2-propenoic acid 4-nitrooxybutyl ester | HCID 9796743 | 70% |
반응 단계
A mixture of potassium (E)-3-(4-hydroxy-3-methoxyphenyl)-2-propenoate (2.07 g; 9 mmol), obtained in the previous step, DMF (8.3 g), KI (0.5 g) and a 20% w/w solution (82.5 g) of 4-bromobutylnitrate (16.5 g; 16.7 mmol) in CH2Cl2 is heated under stirring to 40° C. and kept at this temperature under stirring for 136 h. After work up, (E)-3-(4-hydroxy-3-methoxyphenyl)-2-propenoic acid 4-(nitrooxy)butyl ester was obtained in 70% yield.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07745496B2 |
|---|
| 출처 데이터셋 | uspto-grants-2010_06 |
|---|
| ORD ID | ord-16f4985fa84c43459ff25b3049cc25b1 |
|---|
| 출처 메모 | uspto-grants-2010_06 |
|---|
