4-Methyl-1,3-oxazolidin-2-one → 2-[4-(5-Cyclopropyl-3-methyl-2-pyridinyl)piperazine-1-carbonyl]-5-(4-methyl-2-oxo-1,3-oxazolidin-3-yl)benzonitrile

HRID 200102

반응식

HRID 200102 반응식
[Br:1][c:2]1[cH:3][cH:4][c:5]([C:10](=[O:11])[N:12]2[CH2:13][CH2:14][N:15]([c:18]3[n:19][cH:20][c:21]([CH:25]4[CH2:26][CH2:27]4)[cH:22][c:23]3[CH3:24])[CH2:16][CH2:17]2)[c:6]([C:7]#[N:8])[cH:9]1.[CH3:28][CH:29]1[NH:30][C:31](=[O:34])[O:32][CH2:33]1>>[c:2]1([N:30]2[CH:29]([CH3:28])[CH2:33][O:32][C:31]2=[O:34])[cH:3][cH:4][c:5]([C:10](=[O:11])[N:12]2[CH2:13][CH2:14][N:15]([c:18]3[n:19][cH:20][c:21]([CH:25]4[CH2:26][CH2:27]4)[cH:22][c:23]3[CH3:24])[CH2:16][CH2:17]2)[c:6]([C:7]#[N:8])[cH:9]1

참가 물질

3

반응물 2

HCID 98554554-Methyl-1,3-oxazolidin-2-oneHCID 584845735-Bromo-2-[4-(5-cyclopropyl-3-methylpyridin-2-yl)piperazine-1-carbonyl]benzonitrile

생성물 1

HCID 673811262-[4-(5-Cyclopropyl-3-methyl-2-pyridinyl)piperazine-1-carbonyl]-5-(4-methyl-2-oxo-1,3-oxazolidin-3-yl)benzonitrile

출처 및 근거

ORD 기록
ord-866261e370c14c4aade4786394796fff
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

연결된 노트

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