Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3,4-dihydro-2H-pyran → Diethyl 5-(tetrahydropyran-2-yloxy)pentylphosphonate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3,4-dihydro-2H-pyran | HCID 8080 | — |
| 반응물 | Benzenesulfonic acid, 4-methyl-, compd. with pyridine (1:1) | HCID 466102 | — |
| 반응물 | Diethyl 5-hydroxypentylphosphonate | HCID 10680635 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | Diethyl 5-(tetrahydropyran-2-yloxy)pentylphosphonate | HCID 19689209 | — |
반응 단계
A solution of 66.9 g (0.298 mol) of diethyl 5-hydroxypentylphosphonate, 32.6 g (0.38 mol) of 3,4-dihydropyran and 1 g (0.004 mol) of pyridinium toluene-4-sulfonate in 800 ml of dichloromethane was heated under reflux for 16 hours. The solution was washed with water and saturated sodium hydrogen carbonate solution, dried over sodium sulfate and distilled in a bulb tube.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05728686 |
| 출처 데이터셋 | uspto-grants-1998_03 |
| ORD ID | ord-1e24e4dd0b0641159e1602ba6f4a336e |
| 출처 메모 | uspto-grants-1998_03 |