7-Bromo-3,4-dihydropyrido[2,1-c][1,4]oxazine-1,6-dione → 3,4-Dihydro-7-(4-methyl-1H-imidazol-1-yl)pyrido[2,1-c][1,4]oxazine-1,6-dione

HRID 2014717

반응식

HRID 2014717 반응식
Br[C:1]([C:11](=[O:12])[N:5]1[C:4]([C:9](=[O:10])[O:8][CH2:7][CH2:6]1)=[CH:3]2)=[CH:2]2.[CH3:13][c:14]1[n:18][cH:17][nH:16][cH:15]1>>[CH3:13][c:14]1[n:18][cH:17][n:16]([C:1]([C:11](=[O:12])[N:5]2[C:4]([C:9](=[O:10])[O:8][CH2:7][CH2:6]2)=[CH:3]3)=[CH:2]3)[cH:15]1

참가 물질

8

반응물 2

HCID 1224399027-Bromo-3,4-dihydropyrido[2,1-c][1,4]oxazine-1,6-dioneHCID 178418800HCID 178418800, 화합물

생성물 1

HCID 683801743,4-Dihydro-7-(4-methyl-1H-imidazol-1-yl)pyrido[2,1-c][1,4]oxazine-1,6-dione

시약·촉매·용매 5

HCID 165867Lithium phosphate시약HCID 178422000HCID 178422000, 화합물촉매HCID 1140Toluene용매HCID 312751,4-Dioxane용매HCID 117669-Phenylanthracene내부 표준

반응 조건

온도
100 °C

출처 및 근거

ORD 기록
ord-fbd4f130deb449989096c5262ceb64d0
출처 데이터셋
39k HTE dataset from Pfizer
원본 링크
출처 보기

연결된 노트

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