Tetrahydrofuran → 2-Bromo-1-{(3SR,4RS)-3-(3,4-dichloro-phenyl)-4-[(3-fluoro-4-trifluoromethyl-benzyl)-methyl-amino]-pyrrolidin-1-yl}-ethanone

HRID 201619노트

반응식

[Br:1][CH2:2][C:3](=[O:4])[Cl:5].[CH2:33]([N:34]([CH2:35][CH3:36])[CH2:37][CH3:38])[CH3:39].[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[Cl:6][c:7]1[cH:8][c:9]([CH:14]2[CH:15]([N:19]([CH3:20])[CH2:21][c:22]3[cH:23][c:24]([F:32])[c:25]([C:28]([F:29])([F:30])[F:31])[cH:26][cH:27]3)[CH2:16][NH:17][CH2:18]2)[cH:10][cH:11][c:12]1[Cl:13]>>[Br:1][CH2:2][C:3](=[O:4])[N:17]1[CH2:16][CH:15]([N:19]([CH3:20])[CH2:21][c:22]2[cH:23][c:24]([F:32])[c:25]([C:28]([F:29])([F:30])[F:31])[cH:26][cH:27]2)[CH:14]([c:9]2[cH:8][c:7]([Cl:6])[c:12]([Cl:13])[cH:11][cH:10]2)[CH2:18]1