3-Bromopyrazolo(1,5-a)pyrimidine → (R)-tert-butyl 3-(N-(3-methylpyridin-2-yl)-4-(pyrazolo[1,5-a]pyrimidin-3-yl)benzamido)piperidine-1-carboxylate
반응식
[CH3:1][c:2]1[c:7]([N:8]([C:22]([c:24]2[cH:29][cH:28][c:27](B3OC(C)(C)C(C)(C)O3)[cH:26][cH:25]2)=[O:23])[C@H:9]4[CH2:14][N:13]([C:15]([O:17][C:18]([CH3:21])([CH3:20])[CH3:19])=[O:16])[CH2:12][CH2:11][CH2:10]4)[n:6][cH:5][cH:4][cH:3]1.Br[c:30]1[c:38]([n:33]2[n:32][cH:31]1)[n:37][cH:36][cH:35][cH:34]2>>[CH3:1][c:2]1[c:7]([N:8]([C:22]([c:24]2[cH:29][cH:28][c:27]([c:30]3[c:38]([n:33]4[n:32][cH:31]3)[n:37][cH:36][cH:35][cH:34]4)[cH:26][cH:25]2)=[O:23])[C@H:9]5[CH2:14][N:13]([C:15]([O:17][C:18]([CH3:21])([CH3:20])[CH3:19])=[O:16])[CH2:12][CH2:11][CH2:10]5)[n:6][cH:5][cH:4][cH:3]1참가 물질
8
반응물 2
생성물 1
시약·촉매·용매 5
반응 조건
- 온도
- 80 °C
출처 및 근거
- ORD 기록
- ord-83e71c9211b34efa9980db07a818ac32
- 출처 데이터셋
- 39k HTE dataset from Pfizer
- 원본 링크
- 출처 보기
반응 노트
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