Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Glyoxylic Acid → Alpha-Hydroxyhippuric acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Glyoxylic Acid | HCID 760 | — |
| 반응물 | Benzamide | HCID 2331 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | Alpha-Hydroxyhippuric acid | HCID 450272 | — |
반응 단계
A mixture of commercially available benzamide 35 and glyoxylic acid 41 was heated at reflux in acetone to give pure N-benzoyl-2-hydroxyglycine 65 as a colourless solid in quantitative yield (Scheme 4.12). The 1H n.m.r. spectrum supported formation of the ox-hydroxyglycine derivative 65 with the appearance of a methine (H2) doublet and broad amide (NH) doublet at δ 5.60 and δ 9.26 respectively. Spectroscopic data were in agreement with those reported in the literature.209
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07745573B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-9b741076ad9544a8b379ce92eb9f70b0 |
| 출처 메모 | uspto-grants-2010_06 |