Pyridine → 1,3-dimethyl-N-{3-methyl-5-[(6-{[(4-methylphenyl)sulfonyl]amino}pyridin-3-yl)oxy]phenyl}-1H-pyrazole-5-carboxamide

HRID 202147

반응식

HRID 202147 반응식
[NH2:1][c:2]1[cH:3][cH:4][c:5]([O:8][c:9]2[cH:10][c:11]([NH:16][C:17](=[O:18])[c:19]3[cH:20][c:21]([CH3:25])[n:22][n:23]3[CH3:24])[cH:12][c:13]([CH3:15])[cH:14]2)[cH:6][n:7]1.[c:26]1([CH3:36])[cH:27][cH:28][c:29]([S:32](=[O:33])(=[O:34])[Cl:35])[cH:30][cH:31]1.[cH:37]1[cH:38][cH:39][n:40][cH:41][cH:42]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([O:8][c:9]2[cH:10][c:11]([NH:16][C:17](=[O:18])[c:19]3[cH:20][c:21]([CH3:25])[n:22][n:23]3[CH3:24])[cH:12][c:13]([CH3:15])[cH:14]2)[cH:6][n:7]1)[S:32]([c:29]1[cH:28][cH:27][c:26]([CH3:36])[cH:31][cH:30]1)(=[O:33])=[O:34]

참가 물질

4

반응물 3

HCID 1049PyridineHCID 73974-Toluenesulfonyl chlorideHCID 57749350N-{3-[(6-aminopyridin-3-yl)oxy]-5-methylphenyl}-1,3-dimethyl-1H-pyrazole-5-carboxamide

생성물 1

HCID 577490921,3-dimethyl-N-{3-methyl-5-[(6-{[(4-methylphenyl)sulfonyl]amino}pyridin-3-yl)oxy]phenyl}-1H-pyrazole-5-carboxamide

출처 및 근거

ORD 기록
ord-db572f7f47f749e9a7ea827183a98d2a
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

연결된 노트

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