참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Iodoethane | HCID 6340 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | Diethyl [4-(3-methylxanthin-1-yl)butyl]phosphonate | HCID 22446315 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | Diethyl [4-(7-ethyl-3-methylxanthin-1-yl)butyl]phosphonate | HCID 22446294 | — |
반응 단계
7.2 g (0.02 mol) of diethyl [4-(3-methylxanthin-1-yl)-butyl]phosphonate were suspended in 100 ml of DMF, treated with 4.7 g (0.03 mol) of ethyl iodide and 4.1 g (0.03 mol) of activated potassium carbonate and heated at 60° C. for 4 hours. The solid was filtered off, the filtrate was concentrated under reduced pressure and the oily residue which remained was taken up in ethyl acetate, filtered again and crystallized from diisopropyl ether.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05728686 |
|---|
| 출처 데이터셋 | uspto-grants-1998_03 |
|---|
| ORD ID | ord-056956b73b9f45e9955998f708e34b9b |
|---|
| 출처 메모 | uspto-grants-1998_03 |
|---|
