Benzyl Bromide → 7-Benzyl-3-ethyl-3,7-dihydro-1H-purine-2,6-dione

HRID 2029노트

반응식

HRID 2029 반응식
[CH2:1]([N:3]1[C:11]2[N:10]=[CH:9][NH:8][C:7]=2[C:6](=[O:12])[NH:5][C:4]1=[O:13])[CH3:2].[CH2:14](Br)[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1.C(=O)([O-])[O-].[K+].[K+]>O>[CH2:14]([N:8]1[C:7]2[C:6](=[O:12])[NH:5][C:4](=[O:13])[N:3]([CH2:1][CH3:2])[C:11]=2[N:10]=[CH:9]1)[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1

참가 물질

5

반응물 3

HCID 7498Benzyl BromideHCID 11430Potassium CarbonateHCID 3507373-ethylxanthine

생성물 1

HCID 220073037-Benzyl-3-ethyl-3,7-dihydro-1H-purine-2,6-dione

시약·촉매·용매 1

HCID 962Water용매

실험 절차

18 g (0.1 mol) of 3-ethylxanthine were stirred at 60° C. for 2 hours with 19.2 g (0.11 mol) of benzyl bromide and 15.2 g (0.11 mol) of potassium carbonate. The reaction solution was transferred to an Edenmeyer flask and treated with 1000 ml of water. The precipitate was filtered off with suction, washed several times with warm water and dried at 50° C. under reduced pressure.

후처리

  1. filtrationThe precipitate was filtered off with suction
  2. washwashed several times with warm water
  3. customdried at 50° C. under reduced pressure

출처 및 근거

ORD 기록
ord-61cce6857443438ba8ad80c482010310
출처 데이터셋
uspto-grants-1998_03
특허 번호
US05728686

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