Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl iodide → 1-Ethyl-1-methyl-4-oxopiperidin-1-ium iodide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl iodide | HCID 6328 | — |
| 반응물 | 1-Ethylpiperidin-4-one | HCID 77159 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | 1-Ethyl-1-methyl-4-oxopiperidin-1-ium iodide | HCID 11097568 | 84.9% |
반응 단계
To a solution of 1-ethyl-4-oxopiperidine (25 g, 0.197 mol) in acetone (250 ml) at RT in a water bath was added methyl iodide (15.5 ml, 0.25 mol) at such a rate to keep the temperature below 30° C. The mixture was filtered and the precipitate washed with acetone and dried to yield 1-ethyl-1-methyl-4-oxopiperidinium iodide (45 g) (LC/MS: Rt 0.38, [M+H]+ 143).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07745638B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-ae618f52af61445c9898a909d30788df |
| 출처 메모 | uspto-grants-2010_06 |