1-Fluoro-2,4,6-trimethylpyridinium Tetrafluoroborate (Fluorinating Reagent) → HCID 178508376, 화합물

HRID 2032902노트

반응식

HRID 2032902 반응식
[NH2:1][c:2]1[n:7][cH:6][c:5]([c:8]2[c:16]([c:12]3[n:11][c:10]([N:23]4[C@@H:28]([CH2:29]O)[CH2:27][O:26][CH2:25][CH2:24]4)[n:9]2)[CH2:15][CH2:14][N:13]3[CH:17]5[CH2:22][C:19]([F:21])([F:20])[CH2:18]5)[cH:4][n:3]1.Cc1cc(C)[n+]([F:30])c(C)c1.F[B-](F)(F)F>>[NH2:1][c:2]1[n:7][cH:6][c:5]([c:8]2[c:16]([c:12]3[n:11][c:10]([N:23]4[C@@H:28]([CH2:29][F:30])[CH2:27][O:26][CH2:25][CH2:24]4)[n:9]2)[CH2:15][CH2:14][N:13]3[CH:17]5[CH2:22][C:19]([F:21])([F:20])[CH2:18]5)[cH:4][n:3]1

참가 물질

5

반응물 2

HCID 27793091-Fluoro-2,4,6-trimethylpyridinium Tetrafluoroborate (Fluorinating Reagent)HCID 118444360[(3S)-4-[4-(2-aminopyrimidin-5-yl)-7-(3,3-difluorocyclobutyl)-5,6-dihydropyrrolo[2,3-d]pyrimidin-2-yl]morpholin-3-yl]methanol

생성물 1

HCID 178508376HCID 178508376, 화합물

시약·촉매·용매 2

HCID 6342Acetonitrile용매HCID 117669-Phenylanthracene내부 표준

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온도
25 °C

출처 및 근거

ORD 기록
ord-c3b4b01dce5d474a92ce142123dc7424
출처 데이터셋
39k HTE dataset from Pfizer
원본 링크
출처 보기

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