Vinyl Acetate → 3,3-Dimethyl-1-vinyloxybutane

HRID 20331

반응식

HRID 20331 반응식
[CH3:1][C:2]([CH3:7])([CH3:6])[CH2:3][CH2:4][OH:5].[C:8](OC=C)(=O)[CH3:9].C(=O)([O-])[O-].[Na+].[Na+]>C1C=CC=CC=1.C1CC=CCCC=C1.C1CC=CCCC=C1.[Cl-].[Cl-].[Ir].[Ir]>[CH3:1][C:2]([CH3:7])([CH3:6])[CH2:3][CH2:4][O:5][CH:8]=[CH2:9]

참가 물질

6

반응물 3

HCID 7904Vinyl AcetateHCID 10340Sodium CarbonateHCID 122333,3-Dimethyl-1-butanol

생성물 1

HCID 663680153,3-Dimethyl-1-vinyloxybutane

시약·촉매·용매 2

HCID 6436381Chloro(1,5-cyclooctadiene)iridium(I) dimer촉매HCID 241Benzene용매

실험 절차

Add chloro(1,5-cyclooctadiene)iridium(I) dimer (0.39 g, 0.59 mmol) to 3,3-dimethylbutan-1-ol (3.00 g, 29.35 mmol), vinyl acetate (10.11 g, 117.42 mmol) and sodium carbonate (1.87 g, 17.61 mmol) in benzene (10 mL) at room temperature. Boil under nitrogen 12 hours. Cool to room temperature and filter. Distill the filtrate and collect fraction boiling ˜125° C.-130° C. Flush through a silica gel pad with hexanes and concentrate to provide the title compound.

후처리

  1. custom12 hours
  2. filtrationfilter
  3. distillationDistill the filtrate
  4. customcollect fraction
  5. customboiling ˜125° C.-130° C
  6. customFlush through a silica gel pad with hexanes
  7. concentrationconcentrate

출처 및 근거

ORD 기록
ord-226ce7882d634d20897871d2dacfff1a
출처 데이터셋
uspto-grants-2010_06
특허 번호
US07745438B2

연결된 노트

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