Vinyl Acetate → 3,3-Dimethyl-1-vinyloxybutane
반응식
[CH3:1][C:2]([CH3:7])([CH3:6])[CH2:3][CH2:4][OH:5].[C:8](OC=C)(=O)[CH3:9].C(=O)([O-])[O-].[Na+].[Na+]>C1C=CC=CC=1.C1CC=CCCC=C1.C1CC=CCCC=C1.[Cl-].[Cl-].[Ir].[Ir]>[CH3:1][C:2]([CH3:7])([CH3:6])[CH2:3][CH2:4][O:5][CH:8]=[CH2:9]참가 물질
6
실험 절차
Add chloro(1,5-cyclooctadiene)iridium(I) dimer (0.39 g, 0.59 mmol) to 3,3-dimethylbutan-1-ol (3.00 g, 29.35 mmol), vinyl acetate (10.11 g, 117.42 mmol) and sodium carbonate (1.87 g, 17.61 mmol) in benzene (10 mL) at room temperature. Boil under nitrogen 12 hours. Cool to room temperature and filter. Distill the filtrate and collect fraction boiling ˜125° C.-130° C. Flush through a silica gel pad with hexanes and concentrate to provide the title compound.
후처리
- custom12 hours
- filtrationfilter
- distillationDistill the filtrate
- customcollect fraction
- customboiling ˜125° C.-130° C
- customFlush through a silica gel pad with hexanes
- concentrationconcentrate
출처 및 근거
- ORD 기록
- ord-226ce7882d634d20897871d2dacfff1a
- 출처 데이터셋
- uspto-grants-2010_06
- 특허 번호
- US07745438B2
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