참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 1-Bromo-3-methylbutane | HCID 7891 | — |
| 반응물 | Sodium hydride | HCID 24758 | — |
| 반응물 | 3-Methylxanthine | HCID 70639 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 7-(3-Methylbutyl)-3-methylxanthine | HCID 19689144 | — |
반응 단계
100 g (0.602 mol) of 3-methylxanthine, dissolved in 1200 ml of DMF, were slowly treated with 16 g (0.66 mol) of sodium hydride. The solution was heated to 60° C. and, when the evolution of hydrogen was at an end, treated with 109 g (0.66 mol) of 1-bromo-3-methylbutane. The reaction mixture was stirred at 100° C. for 12 hours and introduced into 2000 ml of water. The precipitate was filtered off with suction, washed with water and dried to constant weight.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05728686 |
|---|
| 출처 데이터셋 | uspto-grants-1998_03 |
|---|
| ORD ID | ord-53dbbec3515e46f1bf52497ce7ab8115 |
|---|
| 출처 메모 | uspto-grants-1998_03 |
|---|
