(Oxolan-3-yl)methanamine hydrochloride → HCID 67224141, 화합물

HRID 2036344노트

반응식

HRID 2036344 반응식
[CH2:1]([O:5][C:6]1[N:14]=[C:13]2[C:9]([N:10]=[C:11]([O:24][CH3:25])[N:12]2[CH2:15][CH2:16][CH2:17][NH:18][C@@H:19]2[CH2:23][CH2:22][CH2:21][O:20]2)=[C:8]([NH2:26])[N:7]=1)[CH2:2][CH2:3][CH3:4].F[C:28](F)(F)C(O)=O.C(OC1NC(N)=C2C(N=1)=NC(OC)=N2)CCC.Cl.O1CCC(CN)C1>>[CH2:1]([O:5][C:6]1[N:14]=[C:13]2[C:9]([N:10]=[C:11]([O:24][CH3:25])[N:12]2[CH2:15][CH2:16][CH2:17][NH:18][CH2:19][CH:23]2[CH2:22][CH2:21][O:20][CH2:28]2)=[C:8]([NH2:26])[N:7]=1)[CH2:2][CH2:3][CH3:4]

참가 물질

4

반응물 3

HCID 17750392(Oxolan-3-yl)methanamine hydrochlorideHCID 672246862-(Butyloxy)-8-(methyloxy)-9-{3-[(2S)-tetrahydro-2-furanylamino]propyl}-9H-purin-6-amineHCID 178450357HCID 178450357, 화합물

생성물 1

HCID 67224141HCID 67224141, 화합물

실험 절차

Prepared similarly to Intermediate 14 from 2-(butyloxy)-8-(methyloxy)-1H-purin-6-amine trifluoroacetate and (tetrahydro-3-furanylmethyl)amine hydrochloride.

출처 및 근거

ORD 기록
ord-1a17005db2374f0298009f087d6edd35
출처 데이터셋
uspto-grants-2013_11
특허 번호
US08575181B2

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