6-Isobutyl-4-methoxy-pyridine-2-carboxylic acid → 2-Ethyl-4-[5-(6-isobutyl-4-methoxy-pyridin-2-yl)-[1,3,4]oxadiazol-2-yl]-6-methyl-phenol
반응식
[CH2:1]([C:5]1[N:10]=[C:9]([C:11]([OH:13])=O)[CH:8]=[C:7]([O:14][CH3:15])[CH:6]=1)[CH:2]([CH3:4])[CH3:3].C([O:23][C:24]1[C:33]([CH3:34])=[CH:32][C:27]([C:28]([NH:30][NH2:31])=O)=[CH:26][C:25]=1[CH2:35][CH3:36])C1C=CC=CC=1>>[CH2:35]([C:25]1[CH:26]=[C:27]([C:28]2[O:13][C:11]([C:9]3[CH:8]=[C:7]([O:14][CH3:15])[CH:6]=[C:5]([CH2:1][CH:2]([CH3:3])[CH3:4])[N:10]=3)=[N:31][N:30]=2)[CH:32]=[C:33]([CH3:34])[C:24]=1[OH:23])[CH3:36]참가 물질
3
실험 절차
The title compound is prepared in analogy to Example 18 starting from 6-isobutyl-4-methoxy-pyridine-2-carboxylic acid and 4-benzyloxy-3-ethyl-5-methyl-benzoic acid hydrazide; LC-MS: tR=1.04 min, [M+H]+=368.33.
출처 및 근거
- ORD 기록
- ord-8610cb6657f54f12a6adb3176730f66c
- 출처 데이터셋
- uspto-grants-2013_11