5-Isobutyl-4-methylpyridine-2-carboxylic acid → 2-Ethyl-4-[5-(5-isobutyl-4-methyl-pyridin-2-yl)-[1,3,4]oxadiazol-2-yl]-6-methyl-phenol
반응식
[CH2:1]([C:5]1[C:6]([CH3:14])=[CH:7][C:8]([C:11]([OH:13])=O)=[N:9][CH:10]=1)[CH:2]([CH3:4])[CH3:3].C([O:22][C:23]1[C:32]([CH3:33])=[CH:31][C:26]([C:27]([NH:29][NH2:30])=O)=[CH:25][C:24]=1[CH2:34][CH3:35])C1C=CC=CC=1>>[CH2:34]([C:24]1[CH:25]=[C:26]([C:27]2[O:13][C:11]([C:8]3[CH:7]=[C:6]([CH3:14])[C:5]([CH2:1][CH:2]([CH3:3])[CH3:4])=[CH:10][N:9]=3)=[N:30][N:29]=2)[CH:31]=[C:32]([CH3:33])[C:23]=1[OH:22])[CH3:35]참가 물질
3
실험 절차
The title compound is prepared in analogy to Example 18 starting from 5-isobutyl-4-methyl-pyridine-2-carboxylic acid and 4-benzyloxy-3-ethyl-5-methyl-benzoic acid hydrazide; LC-MS: tR=1.07 min, [M+H]+=357.18.
출처 및 근거
- ORD 기록
- ord-3caa308f439949bd9bca1a48086aa8cd
- 출처 데이터셋
- uspto-grants-2013_11