3-Piperidineethanol → Benzyl 3-(2-hydroxyethyl)piperidine-1-carboxylate

HRID 2038166노트

반응식

HRID 2038166 반응식
OCCC[CH:5]1[CH2:10][CH2:9][CH2:8][CH2:7][N:6]1[C:11]([O:13][CH2:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)=[O:12].N1CCCC([CH2:27][CH2:28][OH:29])C1>>[OH:29][CH2:28][CH2:27][CH:8]1[CH2:9][CH2:10][CH2:5][N:6]([C:11]([O:13][CH2:14][C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=2)=[O:12])[CH2:7]1

참가 물질

3

반응물 2

HCID 27627163-PiperidineethanolHCID 58306067Benzyl 2-(3-hydroxypropyl)piperidine-1-carboxylate

생성물 1

HCID 13971207Benzyl 3-(2-hydroxyethyl)piperidine-1-carboxylate

실험 절차

Prepared similarly to Intermediate 9 from 2-(3-piperidinyl)ethanol (commercially available, for example from Tyger).

출처 및 근거

ORD 기록
ord-45f26a75f3834772bd551aa4597f643c
출처 데이터셋
uspto-grants-2013_11
특허 번호
US08575340B2

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