Benzyl 3-(2-hydroxyethyl)piperidine-1-carboxylate → Benzyl 3-(2-bromoethyl)piperidine-1-carboxylate

HRID 2038167노트

반응식

HRID 2038167 반응식
[Br:1]CCCC1CCCCN1C(OCC1C=CC=CC=1)=O.O[CH2:22][CH2:23][CH:24]1[CH2:29][CH2:28][CH2:27][N:26]([C:30]([O:32][CH2:33][C:34]2[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=2)=[O:31])[CH2:25]1>>[Br:1][CH2:22][CH2:23][CH:24]1[CH2:29][CH2:28][CH2:27][N:26]([C:30]([O:32][CH2:33][C:34]2[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=2)=[O:31])[CH2:25]1

참가 물질

3

반응물 2

HCID 13971207Benzyl 3-(2-hydroxyethyl)piperidine-1-carboxylate2회HCID 58306190Benzyl 2-(3-bromopropyl)piperidine-1-carboxylate

생성물 1

HCID 58306150Benzyl 3-(2-bromoethyl)piperidine-1-carboxylate

실험 절차

Prepared similarly to Intermediate 10 from phenylmethyl 3-(2-hydroxyethyl)-1-piperidinecarboxylate (for example, as prepared for Intermediate 15).

출처 및 근거

ORD 기록
ord-1ed850e3e8564846a4069bbf9b8ee4be
출처 데이터셋
uspto-grants-2013_11
특허 번호
US08575340B2

반응 노트

불러오는 중…