Diethyl(4-chlorobutyl)phosphonate → Diethyl [4-(7-ethoxymethyl-3-ethylxanthin-1-yl)butyl]phosphonate

반응식

[CH2:1]([O:3][CH2:4][N:5]1[C:13]2[C:12](=[O:14])[NH:11][C:10](=[O:15])[N:9]([CH2:16][CH3:17])[C:8]=2[N:7]=[CH:6]1)[CH3:2].Cl[CH2:19][CH2:20][CH2:21][CH2:22][P:23]([O:28][CH2:29][CH3:30])(=[O:27])[O:24][CH2:25][CH3:26]>>[CH2:1]([O:3][CH2:4][N:5]1[C:13]2[C:12](=[O:14])[N:11]([CH2:19][CH2:20][CH2:21][CH2:22][P:23](=[O:27])([O:28][CH2:29][CH3:30])[O:24][CH2:25][CH3:26])[C:10](=[O:15])[N:9]([CH2:16][CH3:17])[C:8]=2[N:7]=[CH:6]1)[CH3:2]

참가 물질

반응물 2

HCID 19689195Diethyl(4-chlorobutyl)phosphonate

HCID 19689269HCID 19689269, 화합물

생성물 1

HCID 22446312Diethyl [4-(7-ethoxymethyl-3-ethylxanthin-1-yl)butyl]phosphonate

실험 절차

The title substance was prepared from 0.01 5 mol of 7-ethoxymethyl-3-ethylxanthine and 0.017 mol of diethyl 4-chlorobutanephosphonate analogously to 53.

출처 및 근거

ORD 기록: ord-97646f4f01d04c408248a374735fff7f
출처 데이터셋: uspto-grants-1998_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05728686

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