tert-Butyl 2-(aminomethyl)morpholine-4-carboxylate → HCID 178489243, 화합물
반응식
[CH3:1][O:2][C:3]1[CH:21]=[C:20]([CH:22]=[C:23]2[S:27][C:26](SC)=[N:25][C:24]2=[O:30])[CH:19]=[CH:18][C:4]=1[O:5][C:6]1[CH:13]=[CH:12][C:9]([C:10]#[N:11])=[CH:8][C:7]=1[C:14]([F:17])([F:16])[F:15].[C:31]([O:35][C:36]([N:38]1[CH2:43][CH2:42][O:41][CH:40]([CH2:44][NH2:45])[CH2:39]1)=[O:37])([CH3:34])([CH3:33])[CH3:32]>>[C:31]([O:35][C:36]([N:38]1[CH2:43][CH2:42][O:41][CH:40]([CH2:44][NH:45][C:26]2[S:27][C:23](=[CH:22][C:20]3[CH:19]=[CH:18][C:4]([O:5][C:6]4[CH:13]=[CH:12][C:9]([C:10]#[N:11])=[CH:8][C:7]=4[C:14]([F:17])([F:15])[F:16])=[C:3]([O:2][CH3:1])[CH:21]=3)[C:24](=[O:30])[N:25]=2)[CH2:39]1)=[O:37])([CH3:34])([CH3:33])[CH3:32]참가 물질
3
실험 절차
2-({5-[4-(4-Cyano-2-trifluoromethyl-phenoxy)-3-methoxy-benzylidene]-4-oxo-4,5-dihydro-thiazol-2-ylamino}-methyl)-morpholine-4-carboxylic acid tert-butyl ester was prepared using 4-[2-Methoxy-4-(2-methylsulfanyl-4-oxo-4H-thiazol-5-ylidenemethyl)-phenoxy]-3-trifluoromethyl-benzonitrile and 2-aminomethyl-morpholine-4-carboxylic acid tert-butyl ester as described in Example 5C.
출처 및 근거
- ORD 기록
- ord-06f2aaec476f4f659b0277811f2d8e18
- 출처 데이터셋
- uspto-grants-2013_11
- 특허 번호