3-(3-Chlorophenyl)prop-2-ynal oxime → 3-(3-Chlorophenyl)-N-hydroxy-prop-2-ynimidoyl chloride

HRID 2040863노트

반응식

HRID 2040863 반응식
[OH:1][N:2]=[C:3]([Cl:10])[C:4]#[C:5][Si](C)(C)C.[Cl:11][C:12]1[CH:13]=[C:14](C#CC=NO)[CH:15]=[CH:16][CH:17]=1>>[Cl:11][C:12]1[CH:17]=[C:16]([C:5]#[C:4][C:3]([Cl:10])=[N:2][OH:1])[CH:15]=[CH:14][CH:13]=1

참가 물질

3

반응물 2

HCID 765430563-(3-Chlorophenyl)prop-2-ynal oximeHCID 86662874N-Hydroxy-3-trimethylsilyl-prop-2-ynimidoyl chloride

생성물 1

HCID 866628753-(3-Chlorophenyl)-N-hydroxy-prop-2-ynimidoyl chloride수율 96.4%

실험 절차

The title compound was prepared following the method herein described for Compound 3b, using Compound 31e instead of 3-trimethylsilylprop-2-ynal oxime. The pale brown residue was used in the next step without further purification. Yield: 96.4%.

후처리

  1. customThe pale brown residue was used in the next step without further purification

출처 및 근거

ORD 기록
ord-03511dc42bd04cd281104ee0cfc30fe2
출처 데이터셋
uspto-grants-2013_11
특허 번호
US08580962B2

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