참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Methanimidamide, N,N-diphenyl- | HCID 78296 | — |
| 반응물 | 3-(3-Methoxyphenyl)-3-oxopropanenitrile | HCID 584716 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 2-(3-Methoxybenzoyl)-3-phenylamino-acrylonitrile | HCID 67024286 | — |
반응 단계
A solution of 3-methoxybenzoylacetonitrile (1.20 g, 68.5 mmol, 1.0 eq) and diphenylformamidine (1.34 g, 68.5 mmol, 1.0 eq) in 25 mL of toluene was stirred at room temperature for 2 h then heated to 100° C. overnight. The solution was cooled and diluted with hexanes. The resulting solid was filtered and dried to provide the desired product. HPLC (4 minute 10-90 gradient) tR 3.05 min; MS m/z 279.2 [M+H]+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08580838B2 |
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| 출처 데이터셋 | uspto-grants-2013_11 |
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| ORD ID | ord-9d0861251b884245a988670b15c7d689 |
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| 출처 메모 | uspto-grants-2013_11 |
|---|
