3-Ethyl-7-propylxanthine → Diethyl [5-(3-ethyl-7-propylxanthin-1-yl)pentyl]phosphonate

반응식

[CH2:1]([N:3]1[C:11]2[N:10]=[CH:9][N:8]([CH2:12][CH2:13][CH3:14])[C:7]=2[C:6](=[O:15])[NH:5][C:4]1=[O:16])[CH3:2].Br[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][P:23]([O:28][CH2:29][CH3:30])(=[O:27])[O:24][CH2:25][CH3:26]>>[CH2:1]([N:3]1[C:11]2[N:10]=[CH:9][N:8]([CH2:12][CH2:13][CH3:14])[C:7]=2[C:6](=[O:15])[N:5]([CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][P:23](=[O:27])([O:28][CH2:29][CH3:30])[O:24][CH2:25][CH3:26])[C:4]1=[O:16])[CH3:2]

참가 물질

반응물 2

HCID 98159023-Ethyl-7-propylxanthine

HCID 10924159Diethyl-5-bromopentylphosphonate

생성물 1

HCID 22446296Diethyl [5-(3-ethyl-7-propylxanthin-1-yl)pentyl]phosphonate

실험 절차

The title substance was prepared from 0.0225 mol of 3-ethyl-7-propyl-xanthine and 0.027 mol of diethyl 5-bromopentanephosphonate analogously to Example 46.

출처 및 근거

ORD 기록: ord-b448fa8f2cf14a97b043ce62959c7c5a
출처 데이터셋: uspto-grants-1998_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05728686

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