Ethyl 2-(2-aminothiazol-5-ylthio)acetate → HCID 67049912, 화합물
반응식
C([O:3][C:4](=[O:33])[CH2:5][S:6][C:7]1[S:11][C:10]([NH:12][C:13]([N:15](CC2CCCC2)[C:16]2[CH:21]=[CH:20][CH:19]=[C:18]([C:22](=[O:26])[N:23]([CH3:25])[CH3:24])[CH:17]=2)=[O:14])=[N:9][CH:8]=1)C.[CH:34]1(CN(C2C=CC(S(C)(=O)=O)=CC=2)C(=O)NC2SC=C(CC(O)=O)N=2)[CH2:38][CH2:37][CH2:36][CH2:35]1.[CH:63]1(CNC2C=C(C=CC=2)C(N(C)C)=O)CCCC1.C(OC(=O)CSC1SC(N)=NC=1)C>>[CH:34]1([N:15]([C:16]2[CH:21]=[CH:20][CH:19]=[C:18]([C:22](=[O:26])[N:23]([CH3:24])[CH3:25])[CH:17]=2)[C:13](=[O:14])[N:12]([CH3:63])[C:10]2[S:11][C:7]([S:6][CH2:5][C:4]([OH:3])=[O:33])=[CH:8][N:9]=2)[CH2:38][CH2:37][CH2:36][CH2:35]1참가 물질
5
실험 절차
The title compound was prepared via {2-[3-cyclopentylmethyl-3-(3-dimethylcarbamoylphenyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid ethyl ester in a similar manner as described for the synthesis of {2-[3-cyclopentylmethyl-3-(4-methanesulfonyl-phenyl)-ureido]-thiazol-4-yl}-acetic acid, using 3-(cyclopentylmethyl-amino)-N,N-dimethyl-benzamide and (2-aminothiazol-5-ylsulfanyl)acetic acid ethyl ester