2-Chloropyridine → 5-(4-Methoxy-benzyl)-2-(pyridin-2-yloxymethyl)-6,7-dihydro-5H-pyrazolo[1,5-a]pyrazin-4-one
반응식
[OH:1][CH2:2][C:3]1[CH:21]=[C:6]2[C:7](=[O:20])[N:8]([CH2:11][C:12]3[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[CH:14][CH:13]=3)[CH2:9][CH2:10][N:5]2[N:4]=1.Cl[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][N:24]=1.FC1C=CC(N2CCN3N=C(COC4C=CC=CN=4)C=C3C2=O)=CC=1>>[CH3:19][O:18][C:15]1[CH:16]=[CH:17][C:12]([CH2:11][N:8]2[CH2:9][CH2:10][N:5]3[N:4]=[C:3]([CH2:2][O:1][C:23]4[CH:28]=[CH:27][CH:26]=[CH:25][N:24]=4)[CH:21]=[C:6]3[C:7]2=[O:20])=[CH:13][CH:14]=1참가 물질
4
반응물 3
생성물 1
실험 절차
The compound was prepared from 2-hydroxymethyl-5-(4-methoxy-benzyl)-6,7-dihydro-5H-pyrazolo[1,5-a]pyrazin-4-one and 2-chloropyridine using the method described in the preceding example 53 (5-(4-fluoro-phenyl)-2-(pyridin-2-yloxymethyl)-6,7-dihydro-5H-pyrazolo[1,5-a]pyrazin-4-one).