5-(2-Methoxyphenyl)-1,3-cyclohexanedione → 5-(3-Fluorophenyl)cyclohexane-1,3-dione

반응식

[F:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10](=[O:12])[CH3:11])[CH:5]=[CH:6][CH:7]=1.C[O:14][C:15]1C=CC=C[C:16]=1C1CC(=O)CC(=O)C1>>[F:1][C:2]1[CH:3]=[C:4]([CH:8]2[CH2:16][C:15](=[O:14])[CH2:11][C:10](=[O:12])[CH2:9]2)[CH:5]=[CH:6][CH:7]=1

참가 물질

반응물 2

HCID 171223135-(2-Methoxyphenyl)-1,3-cyclohexanedione

HCID 666910324-(3-Fluoro-phenyl)-but-3-en-2-one

생성물 1

HCID 215517195-(3-Fluorophenyl)cyclohexane-1,3-dione

실험 절차

The title compound was prepared from 4-(3-fluoro-phenyl)-but-3-en-2-one stage 1 (940 mg, 5.73 mmol), following the procedure describing the synthesis of 5-(2-methoxy-phenyl)-cyclohexane-1,3-dione (example 1/a stage 2).

출처 및 근거

ORD 기록: ord-ef002e2b6fbd4657b9193c0b736376e1
출처 데이터셋: uspto-grants-2013_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08592430B2

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