Sodium Acetate → 2-Acetyl-5-(3-fluoro-phenyl)-cyclohexane-1,3-dione

반응식

[F:1][C:2]1[CH:3]=[C:4]([CH:8]2[CH2:13][C:12](=[O:14])[CH2:11][C:10](=[O:15])[CH2:9]2)[CH:5]=[CH:6][CH:7]=1.[C:16]([O-])(=[O:18])[CH3:17].[Na+].C(C1C(=O)CC(C2C=CC(F)=CC=2)CC1=O)(=O)C>>[C:16]([CH:11]1[C:10](=[O:15])[CH2:9][CH:8]([C:4]2[CH:5]=[CH:6][CH:7]=[C:2]([F:1])[CH:3]=2)[CH2:13][C:12]1=[O:14])(=[O:18])[CH3:17]

참가 물질

반응물 3

HCID 517045Sodium Acetate

HCID 215517195-(3-Fluorophenyl)cyclohexane-1,3-dione

HCID 529508832-Acetyl-5-(4-fluoro-phenyl)cyclohexane-1,3-dione

생성물 1

HCID 582693722-Acetyl-5-(3-fluoro-phenyl)-cyclohexane-1,3-dione

실험 절차

The title compound was prepared from 5-(3-fluoro-phenyl)-cyclohexane-1,3-dione (500 mg, 2.48 mmol), example 1/d stage 2, and sodium acetate (204 mg, 2.48 mmol), following the procedure describing the synthesis of 2-acetyl-5-(4-fluoro-phenyl)-cyclohexane-1,3-dione (example 3/a stage 1).

출처 및 근거

ORD 기록: ord-2310c7f9388442068a7fcc8f8020910c
출처 데이터셋: uspto-grants-2013_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08592430B2

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