Sodium Acetate → 2-Acetyl-5-(2-fluoro-phenyl)-cyclohexane-1,3-dione

반응식

[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:8]1[CH2:13][C:12](=[O:14])[CH2:11][C:10](=[O:15])[CH2:9]1.[C:16]([O-])(=[O:18])[CH3:17].[Na+].C(C1C(=O)CC(C2C=CC(F)=CC=2)CC1=O)(=O)C>>[C:16]([CH:11]1[C:12](=[O:14])[CH2:13][CH:8]([C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=2[F:1])[CH2:9][C:10]1=[O:15])(=[O:18])[CH3:17]

참가 물질

반응물 3

HCID 517045Sodium Acetate

HCID 136448415-(2-Fluorophenyl)cyclohexane-1,3-dione

HCID 529508832-Acetyl-5-(4-fluoro-phenyl)cyclohexane-1,3-dione

생성물 1

HCID 582693302-Acetyl-5-(2-fluoro-phenyl)-cyclohexane-1,3-dione

실험 절차

The title compound was prepared from 5-(2-fluoro-phenyl)-cyclohexane-1,3-dione (770 mg, 3.74 mmol), example 1/b stage 2, and sodium acetate (307 mg, 3.74 mmol), following the procedure describing the synthesis of 2-acetyl-5-(4-fluoro-phenyl)-cyclohexane-1,3 dione (example 3/a stage 1).

출처 및 근거

ORD 기록: ord-cb02e57943674e7f8527b2b58d911f7a
출처 데이터셋: uspto-grants-2013_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08592430B2

반응 노트

불러오는 중…