2-Amino-4-ethyl-7-(4-fluoro-phenyl)-7,8-dihydro-6H-quinazolin-5-one → 2-Amino-4-ethyl-7-(4-fluoro-phenyl)-7,8-dihydro-6H-quinazolin-5-one oxime
반응식
[NH2:1][C:2]1[N:11]=[C:10]([CH2:12][CH3:13])[C:9]2[C:8](=O)[CH2:7][CH:6]([C:15]3[CH:20]=[CH:19][C:18]([F:21])=[CH:17][CH:16]=3)[CH2:5][C:4]=2[N:3]=1.NC1N=C(C)C2C(=[N:34][OH:35])CC(C3C=CC(F)=CC=3)CC=2N=1>>[NH2:1][C:2]1[N:11]=[C:10]([CH2:12][CH3:13])[C:9]2[C:8](=[N:34][OH:35])[CH2:7][CH:6]([C:15]3[CH:20]=[CH:19][C:18]([F:21])=[CH:17][CH:16]=3)[CH2:5][C:4]=2[N:3]=1참가 물질
3
실험 절차
The title compound was prepared from 2-amino-4-ethyl-7-(4-fluoro-phenyl)-7,8-dihydro-6H-quinazolin-5-one from stage 3, following the procedure describing the synthesis of 2-amino-7-(4-fluoro-phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one oxime (example 3/a stage 4).
출처 및 근거
- ORD 기록
- ord-36a7e679993844b8a40bdfb176e40974
- 출처 데이터셋
- uspto-grants-2013_11