5-(1,4-Dioxaspiro[4.5]decan-8-yl)pyrazolo[1,5-a]pyrimidin-7-amine → 5-(1,4-Dioxaspiro[4.5]decan-7-yl)pyrazolo[1,5-a]pyrimidin-7-amine

HRID 2047091노트

반응식

HRID 2047091 반응식
O1[C:5]2([CH2:10][CH2:9][CH:8]([C:11]3[CH:16]=[C:15]([NH2:17])[N:14]4[N:18]=[CH:19][CH:20]=[C:13]4[N:12]=3)[CH2:7][CH2:6]2)OCC1.ClC1N2N=CC=C2N=C(C2CCCC3([O:37][CH2:36][CH2:35][O:34]3)C2)C=1.ClC1N2N=CC=C2N=C(C2CCC3(OCCO3)CC2)C=1>>[O:34]1[C:6]2([CH2:5][CH2:10][CH2:9][CH:8]([C:11]3[CH:16]=[C:15]([NH2:17])[N:14]4[N:18]=[CH:19][CH:20]=[C:13]4[N:12]=3)[CH2:7]2)[O:37][CH2:36][CH2:35]1

참가 물질

4

반응물 3

HCID 667334895-(1,4-Dioxaspiro[4.5]decan-8-yl)pyrazolo[1,5-a]pyrimidin-7-amineHCID 866647817-Chloro-5-(1,4-dioxaspiro[4.5]decan-8-yl)pyrazolo[1,5-a]pyrimidineHCID 866647827-Chloro-5-(1,4-dioxaspiro[4.5]decan-7-yl)pyrazolo[1,5-a]pyrimidine

생성물 1

HCID 667335335-(1,4-Dioxaspiro[4.5]decan-7-yl)pyrazolo[1,5-a]pyrimidin-7-amine

실험 절차

5-(1,4-Dioxaspiro[4.5]decan-7-yl)pyrazolo[1,5-a]pyrimidin-7-amine is synthesized in a manner similar to the synthesis of 5-(1,4-dioxaspiro[4.5]decan-8-yl)pyrazolo[1,5-a]pyrimidin-7-amine, but with 7-chloro-5-(1,4-dioxaspiro[4.5]decan-7-yl)pyrazolo[1,5-a]pyrimidine substituted for 7-chloro-5-(1,4-dioxaspiro[4.5]decan-8-yl)pyrazolo[1,5-a]pyrimidine.

출처 및 근거

ORD 기록
ord-38c62bb134aa44d997f8cf916497ab4e
출처 데이터셋
uspto-grants-2013_11
특허 번호
US08591943B2

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