5-(1,4-Dioxaspiro[4.5]decan-8-yl)pyrazolo[1,5-a]pyrimidin-7-amine → HCID 66738291, 화합물

HRID 2047093노트

반응식

HRID 2047093 반응식
NC1N2N=CC=C2N=C(C2CCC(=O)CC2)C=1.O1[C:22]2([CH2:27][CH2:26][CH2:25][CH:24]([C:28]3[CH:33]=[C:32]([NH2:34])[N:31]4[N:35]=[CH:36][CH:37]=[C:30]4[N:29]=3)[CH2:23]2)[O:21]CC1.O1C2(CCC(C3C=C(N)N4N=CC=C4N=3)CC2)OCC1>>[NH2:34][C:32]1[N:31]2[N:35]=[CH:36][CH:37]=[C:30]2[N:29]=[C:28]([CH:24]2[CH2:25][CH2:26][CH2:27][C:22](=[O:21])[CH2:23]2)[CH:33]=1

참가 물질

4

반응물 3

HCID 667334895-(1,4-Dioxaspiro[4.5]decan-8-yl)pyrazolo[1,5-a]pyrimidin-7-amineHCID 667335335-(1,4-Dioxaspiro[4.5]decan-7-yl)pyrazolo[1,5-a]pyrimidin-7-amineHCID 66733850HCID 66733850, 화합물

생성물 1

HCID 66738291HCID 66738291, 화합물

실험 절차

3-(7-Aminopyrazolo[1,5-a]pyrimidin-5-yl)cyclohexanone was synthesized in a manner similar to the synthesis of 4-(7-aminopyrazolo[1,5-a]pyrimidin-5-yl)cyclohexanone, but 5-(1,4-dioxaspiro[4.5]decan-7-yl)pyrazolo[1,5-a]pyrimidin-7-amine substituted for 5-(1,4-dioxaspiro[4.5]decan-8-yl)pyrazolo[1,5-a]pyrimidin-7-amine.

출처 및 근거

ORD 기록
ord-6a199fd3fba4418ea56dcb29638f8709
출처 데이터셋
uspto-grants-2013_11
특허 번호
US08591943B2

반응 노트

불러오는 중…