Tert-butyl 4-(7-(bis((2-(trimethylsilyl)ethoxy)methyl)amino)-3-iodopyrazolo[1,5-a]pyrimidin-5-yl)piperidine-1-carboxylate → tert-Butyl 4-(7-(bis((2-(trimethylsilyl)ethoxy)methyl)amino)-3-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-5-yl)piperidine-1-carboxylate

반응식

C[Si](C)(C)CCOCN(COCC[Si](C)(C)C)[C:8]1[N:13]2[N:14]=[CH:15][C:16](C3C=NN(C)C=3)=[C:12]2N=C(C2CCC(CC(OCC)=O)CC2)C=1.[CH3:45][Si:46]([CH3:84])([CH3:83])[CH2:47][CH2:48][O:49][CH2:50][N:51]([CH2:75][O:76][CH2:77][CH2:78][Si:79]([CH3:82])([CH3:81])[CH3:80])[C:52]1[N:57]2[N:58]=[CH:59][C:60](I)=[C:56]2[N:55]=[C:54]([CH:62]2[CH2:67][CH2:66][N:65]([C:68]([O:70][C:71]([CH3:74])([CH3:73])[CH3:72])=[O:69])[CH2:64][CH2:63]2)[CH:53]=1.C[Si](C)(C)CCOCN(COCC[Si](C)(C)C)C1N2N=CC(I)=C2N=C(C2CCC(CC(OCC)=O)CC2)C=1>>[CH3:45][Si:46]([CH3:84])([CH3:83])[CH2:47][CH2:48][O:49][CH2:50][N:51]([CH2:75][O:76][CH2:77][CH2:78][Si:79]([CH3:82])([CH3:81])[CH3:80])[C:52]1[N:57]2[N:58]=[CH:59][C:60]([C:16]3[CH:15]=[N:14][N:13]([CH3:8])[CH:12]=3)=[C:56]2[N:55]=[C:54]([CH:62]2[CH2:67][CH2:66][N:65]([C:68]([O:70][C:71]([CH3:74])([CH3:73])[CH3:72])=[O:69])[CH2:64][CH2:63]2)[CH:53]=1