5-(Piperidin-4-yl)-3-(quinolin-3-yl)pyrazolo[1,5-a]pyrimidin-7-amine → 3-(1-Methyl-1H-pyrazol-4-yl)-5-(piperidin-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine

반응식

N1CCC(C2C=C(N)N3N=CC(C4C=NC5C(C=4)=CC=CC=5)=C3N=2)CC1.C[Si](C)(C)CCOC[N:33](COCC[Si](C)(C)C)[C:34]1[N:39]2[N:40]=[CH:41][C:42]([C:43]3[CH:44]=[N:45][N:46]([CH3:48])[CH:47]=3)=[C:38]2[N:37]=[C:36]([CH:49]2[CH2:54][CH2:53][N:52](C(OC(C)(C)C)=O)[CH2:51][CH2:50]2)[CH:35]=1.C[Si](C)(C)CCOCN(COCC[Si](C)(C)C)C1N2N=CC(C3C=NC4C(C=3)=CC=CC=4)=C2N=C(C2CCN(C(OC(C)(C)C)=O)CC2)C=1>>[CH3:48][N:46]1[CH:47]=[C:43]([C:42]2[CH:41]=[N:40][N:39]3[C:34]([NH2:33])=[CH:35][C:36]([CH:49]4[CH2:54][CH2:53][NH:52][CH2:51][CH2:50]4)=[N:37][C:38]=23)[CH:44]=[N:45]1