Isonicotinic Acid → N-(4-(Hydroxymethyl)cyclohexyl)isonicotinamide

HRID 2047847

반응식

HRID 2047847 반응식
[NH2:1][CH:2]1[CH2:7][CH2:6][CH:5]([CH2:8][OH:9])[CH2:4][CH2:3]1.[C:10](O)(=[O:17])[C:11]1[CH:16]=[CH:15][N:14]=[CH:13][CH:12]=1>>[OH:9][CH2:8][CH:5]1[CH2:6][CH2:7][CH:2]([NH:1][C:10](=[O:17])[C:11]2[CH:16]=[CH:15][N:14]=[CH:13][CH:12]=2)[CH2:3][CH2:4]1

참가 물질

3

반응물 2

HCID 5922Isonicotinic AcidHCID 424390((1s,4s)-4-Aminocyclohexyl)methanol

생성물 1

HCID 66746905N-(4-(Hydroxymethyl)cyclohexyl)isonicotinamide

실험 절차

Prepared as in Example 24a from (4-Aminocyclohexyl)methanol and isonicotinic acid as a yellow oil (100%). MS 235 (MH+).

출처 및 근거

ORD 기록
ord-2b3d522840f2427f9b5d2696f4e8d267
출처 데이터셋
uspto-grants-2013_11
특허 번호
US08592592B2

연결된 노트

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