참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Formaldehyde | HCID 712 | — |
| 반응물 | Sulfuric Acid | HCID 1118 | — |
| 반응물 | Potassium Iodide | HCID 4875 | — |
| 반응물 | Propargyl alcohol | HCID 7859 | — |
| 반응물 | Diethylamine | HCID 8021 | — |
| 촉매 | Copper Sulfate | HCID 24462 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 4-(Diethylamino)-2-butyn-1-ol | HCID 82735 | 86% |
반응 단계
204 parts by weight of aqueous 55% strength propargyl alcohol, 250 parts by weight of 30% strength aqueous formaldehyde, 161 parts by weight of diethylamine, 1.4 parts by weight of copper sulfate, 2 parts by weight of potassium iodide, 50 parts by weight of water and 115 parts by weight of concentrated sulfuric acid are mixed and brought to pH 5. The mixture is heated for 5 hours at 92° C. and worked up as described. 242 parts by weight of 1-diethylaminobut-2-yn-4-ol are obtained, corresponding to a yield of 86%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04197258 |
|---|
| 출처 데이터셋 | uspto-grants-1980_04 |
|---|
| ORD ID | ord-2d6780dfe1b148b5b4f822b6054aec71 |
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| 출처 메모 | uspto-grants-1980_04 |
|---|
