Sodium Cyanide → HCID 20344097, 화합물

HRID 2049631노트

반응식

HRID 2049631 반응식
Cl[CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[O:9][C:10]1[CH:15]=[CH:14][CH:13]=[C:12]([F:16])[CH:11]=1.[C-:17]#[N:18].[Na+]>C(O)C.O>[F:16][C:12]1[CH:11]=[C:10]([CH:15]=[CH:14][CH:13]=1)[O:9][C:4]1[CH:5]=[CH:6][CH:7]=[CH:8][C:3]=1[CH2:2][C:17]#[N:18]

참가 물질

5

반응물 2

HCID 8929Sodium CyanideHCID 20344102HCID 20344102, 화합물

생성물 1

HCID 20344097HCID 20344097, 화합물

시약·촉매·용매 2

HCID 702Ethanol용매HCID 962Water용매

실험 절차

1-(Chloromethyl)-2-(3-fluorophenoxy)benzene (26.5 g.) was dissolved in 300 ml of ethanol; a solution of sodium cyanide (7.8 g.) in 15 ml of water was added, and the resulting mixture was heated to reflux overnight. The ethanol was evaporated, the residue taken up in water, extracted with ether and the combined ether extracts were dried and concentrated to give the title compound. ##STR13##

후처리

  1. temperaturethe resulting mixture was heated
  2. temperatureto reflux overnight
  3. customThe ethanol was evaporated
  4. extractionextracted with ether
  5. dry with materialthe combined ether extracts were dried
  6. concentrationconcentrated

출처 및 근거

ORD 기록
ord-80b7f065ce434db98481f731fca32278
출처 데이터셋
uspto-grants-1980_04
특허 번호
US04198421

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