Water → HCID 20344091, 화합물

HRID 2049632노트

반응식

HRID 2049632 반응식
[F:1][C:2]1[CH:3]=[C:4]([CH:15]=[CH:16][CH:17]=1)[O:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[CH2:12][C:13]#N.[OH-:18].[K+].[OH2:20]>C(O)C>[F:1][C:2]1[CH:3]=[C:4]([CH:15]=[CH:16][CH:17]=1)[O:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[CH2:12][C:13]([OH:20])=[O:18]

참가 물질

5

반응물 3

HCID 962WaterHCID 14797Potassium HydroxideHCID 20344097HCID 20344097, 화합물

생성물 1

HCID 20344091HCID 20344091, 화합물

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

2-(3-Fluorophenoxy)benzeneacetonitrile (23 g.), dissolved in 80 ml of ethanol, was heated to reflux for 2 hours with a solution of 20 g. potassium hydroxide in 40 ml of water. The ethanol was evaporated, the residue taken up in water, extracted with ether and acidified to give the title compound, m.p. 81°-84°. ##STR14##

후처리

  1. temperaturewas heated
  2. temperatureto reflux for 2 hours with a solution of 20 g
  3. customThe ethanol was evaporated
  4. extractionextracted with ether

출처 및 근거

ORD 기록
ord-edc0a06b9dde40c99ba4058d36da2e78
출처 데이터셋
uspto-grants-1980_04
특허 번호
US04198421

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