Diethyl Ether → 3-Amino-4,5-dicarbomethoxy-2-(p-chlorophenyl)pyrrole hydrochloride
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[NH2:1][CH:2]([C:5]1[CH:10]=[CH:9][C:8]([Cl:11])=[CH:7][CH:6]=1)[C:3]#[N:4].[C:12]([C:16]#[C:17][C:18]([O:20][CH3:21])=[O:19])([O:14][CH3:15])=[O:13].C(OCC)C>CO.C(OCC)C>[ClH:11].[NH2:4][C:3]1[C:16]([C:12]([O:14][CH3:15])=[O:13])=[C:17]([C:18]([O:20][CH3:21])=[O:19])[NH:1][C:2]=1[C:5]1[CH:10]=[CH:9][C:8]([Cl:11])=[CH:7][CH:6]=1참가 물질
5
실험 절차
Starting from 2-amino-2-(p-chlorophenyl)acetonitrile and dicarbomethoxyacetylene, the open-chain intermediate compound is obtained, m.p. 74°-76° C. (from diethyl ether). The title compound is obtained in a 48% overall yield, m.p. 216°-8° C. (from methanol/diethyl ether).
후처리
- customthe open-chain intermediate compound is obtained
출처 및 근거
- ORD 기록
- ord-4a10edd899584959806b3bad7ac9ad14
- 출처 데이터셋
- uspto-grants-1980_04
- 특허 번호
- US04198502
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