Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → [1-(1,3-Dibutylxanthin-7-yl)methyl]dimethylphosphine Oxide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | Phosphine oxide, (chloromethyl)dimethyl- | HCID 74224 | — |
| 반응물 | 1,3-Dibutylxanthine | HCID 101421 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | [1-(1,3-Dibutylxanthin-7-yl)methyl]dimethylphosphine Oxide | HCID 19689263 | — |
반응 단계
5 g (0.01 9 mol) of 1,3-dibutylxanthine were stirred at 80° C. for 6 hours with 2.88 g (0.0228 mol) of chloromethyldimethylphosphine oxide and 3.2 g (0.0228 mol) of potassium carbonate in 80 ml of DMF. The solution was cooled to room temperature and filtered, and the filtrate was concentrated under reduced pressure. The residue which remained was crystallized in petroleum ether/ethyl acetate.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05728686 |
| 출처 데이터셋 | uspto-grants-1998_03 |
| ORD ID | ord-20ece88fc4e64225b2c8a9f117afb490 |
| 출처 메모 | uspto-grants-1998_03 |