2-Furancarbonylisocyanate → 1-{1-(4-[4-Fluorophenyl]-4-oxobutyl)piperid-4-yl}-3-[2-furoyl]urea

HRID 2050032

반응식

HRID 2050032 반응식
[NH2:1][CH:2]1[CH2:7][CH2:6][N:5]([CH2:8][CH2:9][CH2:10][C:11]([C:13]2[CH:18]=[CH:17][C:16]([F:19])=[CH:15][CH:14]=2)=[O:12])[CH2:4][CH2:3]1.[O:20]1[CH:24]=[CH:23][CH:22]=[C:21]1[C:25]([N:27]=[C:28]=[O:29])=[O:26]>>[F:19][C:16]1[CH:17]=[CH:18][C:13]([C:11](=[O:12])[CH2:10][CH2:9][CH2:8][N:5]2[CH2:6][CH2:7][CH:2]([NH:1][C:28]([NH:27][C:25]([C:21]3[O:20][CH:24]=[CH:23][CH:22]=3)=[O:26])=[O:29])[CH2:3][CH2:4]2)=[CH:14][CH:15]=1

참가 물질

3

반응물 2

HCID 110946822-FurancarbonylisocyanateHCID 126085384-Amino-1-(4-[4-fluorophenyl]-4-oxobutyl)piperidine

생성물 1

HCID 203432481-{1-(4-[4-Fluorophenyl]-4-oxobutyl)piperid-4-yl}-3-[2-furoyl]urea

실험 절차

Using a procedure analogous to Example 1, 4-amino-1-(4-[4-fluorophenyl]-4-oxobutyl)piperidine is reacted with 2-furoyl isocyanate to give the title compound.

출처 및 근거

ORD 기록
ord-d2f6d7969d554f4bb63153298c930728
출처 데이터셋
uspto-grants-1980_04
특허 번호
US04199590

연결된 노트

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