Phenethylamine → 3-Methylthiopropan N-2-phenylethylamide

반응식

C[CH2:2][CH2:3][C:4](Cl)=[S:5].[C:7]1([CH2:13][CH2:14][NH2:15])[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1>>[CH3:7][S:5][CH2:4][CH2:3][CH3:2].[C:7]1([CH2:13][CH2:14][NH-:15])[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1

참가 물질

반응물 2

HCID 1001Phenethylamine

HCID 22343826Butanecarbothioyl chloride

생성물 1

HCID 867369493-Methylthiopropan N-2-phenylethylamide

실험 절차

Prepared from 3-methylthiopropionyl chloride (2.76 g) and 2-phenylethylamine (5.04 g) by the method used in Example 10(a). The solid product (3.79 g) was pure by t.l.c. A sample crystallised from aqueous methanol as needles m.p. 56°-59°.

후처리

customA sample crystallised from aqueous methanol as needles m.p. 56°-59°

출처 및 근거

ORD 기록: ord-2c699f3b86d548d88cacea4cb7971600
출처 데이터셋: uspto-grants-1980_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04199568

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