2-Chloro-4,6-diphenyl-1,3,5-triazine → 2-Azido-4,6-diphenyl-s-triazine

HRID 2050234

반응식

HRID 2050234 반응식
Cl[C:2]1[N:7]=[C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[N:5]=[C:4]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[N:3]=1.[N-:20]=[N+:21]=[N-:22].[Na+].[N-]=[N+]=[N-].[Li+]>C(#N)C>[N:20]([C:2]1[N:7]=[C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[N:5]=[C:4]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[N:3]=1)=[N+:21]=[N-:22]

참가 물질

5

반응물 3

HCID 196982-Chloro-4,6-diphenyl-1,3,5-triazineHCID 33557Sodium AzideHCID 88163Lithium azide

생성물 1

HCID 6236432-Azido-4,6-diphenyl-s-triazine수율 88%

시약·촉매·용매 1

HCID 6342Acetonitrile용매

실험 절차

A suspension of 2-chloro-4,6-diphenyl-s-triazine (30 g, 0.112 mol), sodium azide (12.86 g, 0.199 mol) and lithium azide (1.25 g, 0.025 mol) in acetonitrile (550 ml) was stirred at room temperature for 11 days. After filtration, the filtrate on evaporation yielded 6.9 g of 2-azido-4,6-diphenyl-s-triazine, mp 115°-117° C. The residue on extraction with hot heptane, followed by crystallization from heptane, gave an additional 20 g quantity having a mp of 114°-116° C. bringing the total yield of 2-azido-4,6-diphenyl-s-triazine to 26.9 g (88% yield). The melting point and infrared spectrum were identical with that of an authentic sample.

후처리

  1. filtrationAfter filtration
  2. customthe filtrate on evaporation

출처 및 근거

ORD 기록
ord-d13009c8aded4081a490a33541fc3944
출처 데이터셋
uspto-grants-1980_04
특허 번호
US04200721

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