참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Cyclohexanol | HCID 7966 | — |
| 반응물 | Sodium chloroacetate | HCID 23665759 | — |
| 용매 | Dimethyl Sulfoxide | HCID 679 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | Cyclohexoxyacetic acid | HCID 191994 | 83.1% |
반응 단계
A solution of cyclohexanol (1.75 g, 17.5 mmol) in THF was added, and the mixture was warmed to 25° C. for 1 hour. The THF was removed by distillation under vacuum, and a solution of sodium chloroacetate (2.5 g, 22 mmol) in DMSO (50 ml) was added. The reaction mixture was treated as in Example 3 and 2.3 g of product (83% yield) was obtained as a colorless oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05013864 |
|---|
| 출처 데이터셋 | uspto-grants-1991_05 |
|---|
| ORD ID | ord-99afaf4f76f64cd1a8deeac02b9f6403 |
|---|
| 출처 메모 | uspto-grants-1991_05 |
|---|
