Tetrahydrofuran → Tert-butyl 5-chloro-2-{2-[(4-methoxyphenyl)amino]-3,3,3-trifluoropropyl}benzylcarbamate

반응식

[CH2:37]1[O:38][CH2:39][CH2:40][CH2:41]1.[CH3:23][O:24][c:25]1[cH:26][cH:27][c:28]([N:31]=[CH:32][C:33]([F:34])([F:35])[F:36])[cH:29][cH:30]1.[CH:1]([Li:2])([CH2:3][CH3:4])[CH3:5].[Cl:6][c:7]1[cH:8][cH:9][c:10]([CH3:22])[c:11]([CH2:12][NH:13][C:14]([O:15][C:16]([CH3:17])([CH3:18])[CH3:19])=[O:20])[cH:21]1>>[Cl:6][c:7]1[cH:8][cH:9][c:10]([CH2:22][CH:32]([NH:31][c:28]2[cH:27][cH:26][c:25]([O:24][CH3:23])[cH:30][cH:29]2)[C:33]([F:34])([F:35])[F:36])[c:11]([CH2:12][NH:13][C:14]([O:15][C:16]([CH3:17])([CH3:18])[CH3:19])=[O:20])[cH:21]1