HCID 14422542, 화합물 → Imidazo[1,5-a]pyridine-3-sulfonamide

HRID 2051131노트

반응식

HRID 2051131 반응식
C([NH:5][S:6]([C:9]1[N:13]2[CH:14]=[CH:15][CH:16]=[CH:17][C:12]2=[CH:11][N:10]=1)(=[O:8])=[O:7])(C)(C)C>FC(F)(F)C(O)=O>[CH:11]1[N:10]=[C:9]([S:6]([NH2:5])(=[O:8])=[O:7])[N:13]2[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=12

참가 물질

3

반응물 1

HCID 14422542HCID 14422542, 화합물

생성물 1

HCID 19832737Imidazo[1,5-a]pyridine-3-sulfonamide수율 77.1%

시약·촉매·용매 1

HCID 6422Trifluoroacetic acid용매

실험 절차

N-(t-Butyl)imidazo[1,5-a]pyridine-3-sulfonamide (1.0 g) is dissolved in 20 ml of trifluoroacetic acid and stirred for 14 days at room temperature. The mixture is concentrated under reduced pressure, and ether is added to the residue to precipitate crystals. The crystals are collected by filtration and dried to give 0.60 g of the title compound. mp. 179°-180° C.

후처리

  1. concentrationThe mixture is concentrated under reduced pressure, and ether
  2. additionis added to the residue
  3. customto precipitate crystals
  4. filtrationThe crystals are collected by filtration
  5. customdried

출처 및 근거

ORD 기록
ord-93a5aa6cf675491eb5055d96c4015b00
출처 데이터셋
uspto-grants-1991_05
특허 번호
US05017212

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