Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanol → N-(4-anilinophenyl)-N-(1,3-dimethyl-butyl)-thiocarbamate-O-methyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | Thiophosgene | HCID 10040 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 1,4-Benzenediamine, N-(1,3-dimethylbutyl)-N'-phenyl- | HCID 13101 | — |
| 반응물 | Pyrrolidine | HCID 31268 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | N-(4-anilinophenyl)-N-(1,3-dimethyl-butyl)-thiocarbamate-O-methyl ester | HCID 19832480 | — |
반응 단계
N-phenyl-N'-(1,3-dimethylbutyl)-p-phenylenediamine (26.8g, 0.10 mol) in 100 mL chloroform and 30g (0.22 mol) of K2CO3 as a saturated aqueous solution are placed in a 250 mL, 3-neck round bottom flask. Thiophosgene (11.5g: 0.10 mol) in 20 mL chloroform is added at such a rate sufficient to reach and maintain reflux conditions. Stirring is continued until the mixture returns to room temperature. Methanol (6.4g, 0.2 mol) is then added and the mixture refluxed for 4 hours. The organic layer is separated, dried with MgSO4 and the solvent removed on a rotary evaporator to give the desired product.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05019611 |
| 출처 데이터셋 | uspto-grants-1991_05 |
| ORD ID | ord-0d6a7e843f8543d29cec7e28e8e1f0d9 |
| 출처 메모 | uspto-grants-1991_05 |