5-Methylfurfural → 1-(5-Methyl-furfurylideneamino)-2,3-dioxo-piperazine

HRID 2051763

반응식

HRID 2051763 반응식
[NH2:1][N:2]1[CH2:7][CH2:6][NH:5][C:4](=[O:8])[C:3]1=[O:9].[CH3:10][C:11]1[O:17][C:14]([CH:15]=O)=[CH:13][CH:12]=1>C(O)(=O)C>[CH3:15][C:14]1[O:17][C:11]([CH:10]=[N:1][N:2]2[CH2:7][CH2:6][NH:5][C:4](=[O:8])[C:3]2=[O:9])=[CH:12][CH:13]=1

참가 물질

4

반응물 2

HCID 120975-MethylfurfuralHCID 221847681-Aminopiperazine-2,3-dione

생성물 1

HCID 541207691-(5-Methyl-furfurylideneamino)-2,3-dioxo-piperazine수율 76.6%

시약·촉매·용매 1

HCID 176Acetic Acid용매

실험 절차

1.3 pts. by wt. of 1-amino-2,3-dioxo-piperazine, 1.3 pts. by wt. of 5-methyl-furfural and 7 pts. by vol. of glacial acetic acid are warmed to 90° C. for 10 minutes and then left for 30 minutes at RT. The precipitate is filtered off, washed first with 3 pts. by vol. of glacial acetic acid and then three times with 10 pts. by vol. of ethyl acetate and dried in air. 1.7 pts. by wt. (76.6%) of 1-(5-methyl-furfurylideneamino)-2,3-dioxo-piperazine of decomp. pt. 245°-8° C. are obtained.

후처리

  1. filtrationThe precipitate is filtered off
  2. washwashed first with 3 pts
  3. dry with materialby vol. of ethyl acetate and dried in air

출처 및 근거

ORD 기록
ord-62accbe3162e4c538cc51b0360ed8db8
출처 데이터셋
uspto-grants-1980_01
특허 번호
US04182762

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