5-Bromofuran-2-carbaldehyde → 1-(5-Bromofurfurylideneamino)-2,3-dioxo-piperazine
반응식
[Br:1][C:2]1[O:8][C:5]([CH:6]=O)=[CH:4][CH:3]=1.[NH2:9][N:10]1[CH2:15][CH2:14][NH:13][C:12](=[O:16])[C:11]1=[O:17]>C(O)(=O)C>[Br:1][C:2]1[O:8][C:5]([CH:6]=[N:9][N:10]2[CH2:15][CH2:14][NH:13][C:12](=[O:16])[C:11]2=[O:17])=[CH:4][CH:3]=1참가 물질
4
실험 절차
1.9 pts. by wt. of 5-bromofurfural, 1.3 pts. by wt. of 1-amino-2,3-dioxo-piperazine and 7 pts. by vol. of glacial acetic acid were warmed to 90° for 10 minutes and then left for 30 minutes at RT. The precipitate is filtered off, washed with 3 pts. by vol. of glacial acetic acid and recrystallised from dimethylformamide, with the addition of animal charcoal. 1.1 pts. by wt. (38.5%) of 1-(5-bromofurfurylideneamino)-2,3-dioxo-piperazine are obtained as yellowish crystals of decomp. pt. 220°.
후처리
- filtrationThe precipitate is filtered off
- washwashed with 3 pts
- customby vol. of glacial acetic acid and recrystallised from dimethylformamide, with the addition of animal charcoal
출처 및 근거
- ORD 기록
- ord-cb56760e2339460492f6caaafb119889
- 출처 데이터셋
- uspto-grants-1980_01
- 특허 번호
- US04182762
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