Formic Acid → Phosphoramidic dichloride, (4-butoxybenzoyl)-
반응식
[CH2:1]([O:5][C:6]1[CH:14]=[CH:13][C:9]([C:10]([NH2:12])=[O:11])=[CH:8][CH:7]=1)[CH2:2][CH2:3][CH3:4].[P:15]([Cl:20])(Cl)(Cl)(Cl)[Cl:16].C(O)=[O:22]>C(Cl)(Cl)(Cl)Cl>[CH2:1]([O:5][C:6]1[CH:14]=[CH:13][C:9]([C:10]([NH:12][P:15]([Cl:20])([Cl:16])=[O:22])=[O:11])=[CH:8][CH:7]=1)[CH2:2][CH2:3][CH3:4]참가 물질
5
실험 절차
A mixture of 76 g (0.39 mole) of 4-butoxybenzamide, 81.9 g (0.39 mole) of phosphorus pentachloride and 700 ml of AR carbon tetrachloride was heated at 70° for 30 min. The resulting solution was cooled to 30° and 18.7 g (0.39 mole) of 97% formic acid was added. The reaction was chilled to 0°, filtered, washed with AR carbon tetrachloride and air-dried to give 52.1 g, m.p. 97°-98°.
후처리
- temperaturewas heated at 70° for 30 min
- temperatureThe resulting solution was cooled to 30°
- temperatureThe reaction was chilled to 0°
- filtrationfiltered
- washwashed with AR carbon tetrachloride
- customair-dried
- customto give 52.1 g, m.p. 97°-98°
출처 및 근거
- ORD 기록
- ord-67b734de37604d66875341da34177a27
- 출처 데이터셋
- uspto-grants-1980_01
- 특허 번호
- US04182881
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